Alumni Association
Welcome to the CUNY School of Medicine Alumni Association
CUNY School of Medicine/Sophie Davis Biomedical Education Program alumni have changed the face of medicine. As alumni, you are leaders in your field who have helped to reduce health disparities, enhance health equity, and provide access to compassionate care to medically under-resourced communities. We are proud to serve you and to promote the interests of the CUNY School of Medicine.
Our Prestigious Alumni Are Leaders in Their Fields
The Alumni Association at the CUNY School of Medicine seeks to engage alumni through mentoring services for our medical students, foster fellowship among our alumni, encourage alumni giving, and enhance opportunities to network.
ALUMNI Association Board
Marina Frimer ’05
President
Marina Frimer ’05
President
Bio:
Dr. Abreu began a life-long love of helping others with their health as an Emergency Medical Technician. Soon thereafter she manifested her desire to teach others as an EMT lab instructor. Having a passion for holistic wellness and healthcare, she became a Doctor of Chiropractic with a focus on helping patients restore and maintain good health. Dr. Abreu has further specialized in nutritional assessment and counseling, and is a Certified Health Coach by the National Society of Health Coaches. After 14 years of private practice, she once again embraced her love of teaching here at the CUNY School of Medicine.
Education:
Doctor of Chiropractic, 1999, Life University, Georgia
Certified Health Coach, 2015, National Society of Health Coaches
- Phone:212-650-6579
- Email:[email protected]
Akeem Marsh ’07
Secretary/Treasurer
Akeem Marsh ’07
Secretary/Treasurer
Bio:
Dr. Abreu began a life-long love of helping others with their health as an Emergency Medical Technician. Soon thereafter she manifested her desire to teach others as an EMT lab instructor. Having a passion for holistic wellness and healthcare, she became a Doctor of Chiropractic with a focus on helping patients restore and maintain good health. Dr. Abreu has further specialized in nutritional assessment and counseling, and is a Certified Health Coach by the National Society of Health Coaches. After 14 years of private practice, she once again embraced her love of teaching here at the CUNY School of Medicine.
Education:
Doctor of Chiropractic, 1999, Life University, Georgia
Certified Health Coach, 2015, National Society of Health Coaches
- Phone:212-650-6579
- Email:[email protected]
Sujana Chandrasekhar ’84
Past President
Sujana Chandrasekhar ’84
Past President
Bio:
Dr. Abreu began a life-long love of helping others with their health as an Emergency Medical Technician. Soon thereafter she manifested her desire to teach others as an EMT lab instructor. Having a passion for holistic wellness and healthcare, she became a Doctor of Chiropractic with a focus on helping patients restore and maintain good health. Dr. Abreu has further specialized in nutritional assessment and counseling, and is a Certified Health Coach by the National Society of Health Coaches. After 14 years of private practice, she once again embraced her love of teaching here at the CUNY School of Medicine.
Education:
Doctor of Chiropractic, 1999, Life University, Georgia
Certified Health Coach, 2015, National Society of Health Coaches
- Phone:212-650-6579
- Email:[email protected]
QiLi Li ’94
Education
Ph.D., 1979, St. John's University
M.S., 1970, Fordham University
B.S., 1963, St. Thomas Aquinas College
Postdoctoral Positions:
Dept. of Psychiatry & Neuroscience, Albert Einstein College of Medicine, NY Dept. of Neurology, Cornell University School of Medicine, NY
Research Interests
Development of miniature biosensors for the detection of neurotransmitters and other biologically active compounds such as ascorbic acid, peptides, precursors and metabolites. These BRODERICK PROBE® biosensors allow the study of dynamic changes in neurotransmitters in vivo and in real time, on line with behavioral models as well as on line Neuromolecular Imaging (NMI) with biosensors with cerebral blood flow studies of stroke in animal models.
Studies of cocaine, caffeine, hypoxia, calcium channel blockers, hypotension and nitroglycerin are underway. Ongoing significant advances have been made with these biosensors in human studies in epilepsy patients beginning in 2008 during intraoperative diagnosis of temporal lobe epilepsy with Internal Review Board Approval, NYU, Tisch Hospital , NY.
Pharmacotherapeutic approaches to the treatment of cocaine abuse, caffeine mechanisms, pain, affective disorders, epilepsy, tumors, schizophrenia, Parkinson's disease, post-operative cognitive diseases, drug addiction, oxidative stress, inflammation, cytokines, hypertension, hypoxia, calcium channel blockers, nitroglycerin, ascorbic acid, peptides, stress, enkephalins, dynorphin, morphine, diabetes, Fawn-Hooded animal models, Chediak-Higashi Syndrome.
Publications
Peer-Reviewed Articles
Broderick, P.A., Doyle, W.K., Pacia, S.V., Kuzniecky, R.I., Devinsky, O, and Kolodny, E.H., A clinical trial of an advanced diagnostic biomedical device for epilepsy patients. Journal of Long-Term Effects of Medical Implants, In Press, (2009).
Broderick, P.A., Ho, H., Wat, K. and Murthy, V., Laurate biosensors image brain neurotransmitters in vivo: Can an antihypertensive medication alter psychostimulant behavior? Sensors 8: 4033-4061 (2008).
Broderick, P.A., Studies of oxidative stress mechanisms using a morphine/ascorbate animal model and novel N-stearoyl cerebroside and laurate sensors. J. Neural Transm. 115: 7-17 (2008).
Nunes, J.V. and Broderick, P.A., Novel research translates to clinical cases of schizophrenic and cocaine psychosis. Neuropsychiatric Disease and Treatment 3(4): 475-485 (2007).
Broderick, P.A.; Pacia, S.V. Identification, diagnosis, and treatment of neuropathologies, neurotoxicities, tumors and brain and spinal cord injuries using microelectrodes with microvoltammetry. 2006, U.S. Patent # 7,112,319. Issued, Sept. 26th (2006).
Broderick, P.A. and Hope, O., Monoamines and motor responses are co-deficient in the Fawn-Hooded depressed animal model. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 30: 887-898 (2006).
Simmons, D.A. and Broderick, P.A.. Cytokines, stressors and clinical depression: augmented adaptation responses underlie depression pathogenesis. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 29: 793-807 (2005).
Broderick, P.A., Olabisi, O.A., Rahni, D.N. and Zhou, Y., Cocaine acts on accumbens monoamines and locomotor behavior via a 5-HT2A/2C receptor mechanism as shown by ketanserin: 24 hr follow-up studies. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 28: 547-557 (2004).
Broderick, P.A., Hope, O., Okonji, C., Rahni, D.N. and Zhou, Y., Clozapine and cocaine effects on dopamine and serotonin release in nucleus accumbens during psychostimulant behavior and withdrawal. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 28: 157-171 (2004).
Broderick, P.A., Rahni, D.N. and Zhou, Y., Acute and subacute effects of risperidone and cocaine on accumbens dopamine and serotonin release using in vivo microvoltammetry on line with open-field behavior. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 27: 1037-1054 (2003).
Broderick, P. A. Interieukin 1a alters hippocampal serotonin (5-HT) and norepinephrine (NE) release during open-field behavior in Sprague Dawley animals: Differences from the Fawn-Hooded animal model of depression. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 26: 1355-1372 (2002).
Pacia, S. V., Doyle, W. K. and Broderick, P. A., Biogenic amines in resected human neocortex in patients with neocortical and mesial temporal lobe epilepsy; Identification with in situ microvoltammetry. Brain Research 899:106-111 (2001)
Broderick, P. A., Pacia, S. V., Doyle, W. K. and Devinsky, O., Monoamine neurotransmitters in resected hippocampal subparcellations from neocortical and mesial temporal lobe epilepsy patients: In situ microvoltammetric studies. Brain Research 878:48-63 (2000)
Broderick,P.A., Microelectrodes and their use in a cathodic electrochemical current arrangement with telemetric application. Canadian Patent and PCT # 2,063,607. Issued Nov. 24th(2000).
Broderick, P.A., Microelectrodes and their use in a cathodic electrochemical current arrangement with telemetric application. U.S. Patent # 5,938,903. Issued, Aug. 17th (1999). Broderick, P.A., Microelectrodes and their use in a cathodic electrochemical current arrangement with telemetric application. Hong Kong, The People's Republic of China, Patent # HK 1007350. Issued, Aug. 9th (1999).
Broderick, P. A. and Piercey, M. F., Neurochemical and behavioral evidence supporting (+)-AJ 76 as a potential pharmacotherapy for cocaine abuse. J. Neural Transm. 105: 1307-1324 (1998).
Broderick, P. A. and Piercey, M. F., Clozapine, haloperidol and the D4 antagonist PNU-101387G: In vivo effects on mesocortical, mesolimbic and nigrostriatal dopamine and serotonin release. J. Neural Transm. 105:749-767 (1998).
Broderick, P. A., Hope, O. and Jeannot, P. Mechanism of triazolo-benzodiazepine and benzodiazepine action in anxiety and depression: behavioral studies with concomitant in viro CA1 hippocampal norepinephrine and serotonin release detection in the behaving animal. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 22:353-386 (1998).
Book Chapters
Simmons, D.A. and Broderick, P.A.. Cytokines, stressors and clinical depression: augmented adaptation responses underlie depression pathogenesis. In: Selective Affective Disorders and Schizophrenia.Prog. Neuro-Psychopharmacol. & Biol. Psychiat.(Eds. Broderick, P.A. and Glazer, W.M.) 29: 793-807 (2005).
Pacia, S.V. and Broderick, P.A., Bioimaging L-Tryptophan in human hippocampus and neocortex subtyping temporal lobe epilepsy with microvoltammetry.In: Bioimaging in Neurodegeneration(Eds. Broderick, P.A., Rahni, D.N. and Kolodny, E.H.) Humana Press Inc., Totowa, NJ, pp. 141-147 (2005).
Broderick, P.A., Rahni, D.N. and Pacia, S.V., Nano-and microimaging surgical anesthesia in epilepsy patients. In: Bioimaging in Neurodegeneration (Eds. Broderick, P.A., Rahni, D.N. and Kolodny, E.H.) Humana Press Inc.., pp. xiii-Totowa, NJ, pp. xiii-xvi (2005).
Broderick, P.A. and Pacia, S. V., Imaging white matter signals in epilepsy patients: A unique sensor technology. In: Bioimaging in Neurodegeneration (Eds. Broderick, P.A., Rahni, D.N. and Kolodny, E.H.) Humana Press Inc., Totowa, NJ, pp.199-206 (2005).
Broderick, P.A., Microsensors detect cocaine neuroadaptation: Serotonin release within basal ganglia is not rhythmic with movement. In: Handbook of Neurotoxicology (Eds. Massaro, E.J., Schardein, J.L., Broderick, P.A., Schlaepfer, T.E. and Mattsson, J.L.) Humana Press Inc., Totowa, NJ, 2: pp.323-367 (2002).
Grants/Contracts
Broderick, P.A. Research Grant, Center for Advanced Technology, CCNY, CUNY, NY State Project, ($7500) (2013).
Broderick, P.A. Travel Award, HEKA Electronics Inc., Nova Scotia, Canada, ($3000) (2012)
Broderick, P.A. Research Grants and Licensing Fee, HEKA Electronics, Inc., NY, Germany, Canada, ($117,000) (2013).
Broderick, P.A. Grants from the Anesthesiology Dept., NYU Langone to support part-time technician and support collaboration on Neuromolecular Imaging, hypoxic hypoxia and cognitive decline post-operatively about $100,000-in personnel and supplies (2007-2010).
Broderick, P.A., NYU Langone: Translational work in vivo during epilepsy surgery. IRB (2008) obtained by Dr. Ruben Kuzniecky, Epileptologist, Director of Research, Comprehensive Epilepsy Center, NYU Langone, Dept. of Neurology. This approved project allows use of BRODERICK PROBE® biosensors (manufactured on site, CCNY, NY and Autolab Potentiostat (Metrohm, aka Brinkmann, LI, NY). Amount, immeasurable (2008-present)
Broderick, P.A. NYU, FACES, Foundation for Children with Epileptic Seizures. Neuromolecular imaging in epilepsy and tumor patients intraoperatively using The BRODERICK PROBE® biosensors. ($35, 000).
Broderick, P. A. FM Kirby Foundation: Anti-Platelet Therapy in Ischemic Stroke: Imaging Real Time Neurochemical Changes in Brain. ($125,000.00, 2008-2011).
Kolodny, E.H., Broderick, P.A. Leon Lowenstein Foundation: Gene Therapy in Parkinson's Disease. ($57,255), Sept. 2007 – Dec., 2009).
Previous Additional Sources of Support (2003-2004):
Broderick, P.A., P.I., Student Scholarship Fund: H.S. Student Training: CNS studies.
Broderick, P.A., P.I., Stevens, Davis, Miller and Mosher, LLC: Patent Consult: CNS studies.
Broderick, P.A., P.I., Pharmacia Upjohn Award: CNS research; psychosis, depression, drug abuse.
Broderick, P.A., P.I., Grant and Consultation Support (2002-2004):Codman & Shurtleff, J&J, Broderick Biotechnology.
Broderick, P.A., P.I., Professional Staff Congress, CUNY (2002-2003): Nitrous and Nitric Oxide studies.
National Institute of Health, Foundation and Industrial Support:
Source: National Institutes of Health, NIGMS: SCORE AWARD.
Title: Normal vs. Psychotic Behavior: Neural Basis for Clozapine.
PI: Patricia A. Broderick, Ph.D.
Dates 02/01/00 - 01/31/03
Award: $475,000.00
Source: Parents against Childhood Epilepsy: P.A.C.E. AWARD.
Title: In Vivo Voltammetry with Microelectrodes for the Detection and Quantification of Neurotransmitters in Epileptogenic Cortex during Epilepsy Surgery.
Co-PI: Patricia A. Broderick, Ph.D.
Co-PI: Steven V. Pacia, M.D.
Dates: 12/15/99 - 8/30/01
Award: $52,568. 00
Source: The Pharmacia and Upjohn Company, (Clinical Division: Educational Award).
Title: Brain Neurotransmitter Signals for Diagnosis and Treatment of Central Nervous System Disorders: Psychotic, Affective, Cognitive and Epileptogenic.
PI: Patricia A. Broderick, Ph.D.
Dates: 9/1/1997-unrestricted time period.
Award: $10,000. 00
Grants: Research Support (1985-1999) (Award amounts are written in direct costs; indirect costs are not shown):
Source: The Aaron Diamond Foundation
Title: The Study of a Neuroimmune Link Between AIDS-Related, Interleukin-1 (IL-1) and the Excitotoxin, Quinolinic Acid: Signal Intercommunication in the Hippocampal Serotonergic Neurotransmitter Circuitry.
PI: Patricia A. Broderick, Ph.D. Co-Inv.: Richard Coico, Ph.D. Dates: 10/15/92 - 1/7/95 Award: $143,500. 00 Source: Foundation for Children with Epileptic Seizures: FACES AWARD. Title: Neurotransmitter Release at the Human Epileptogenic Focus: In Situ Studies. PI: Patricia A. Broderick, Ph.D. Dates: 11/15/96 - 6/30/99 Award: $50,000. 00 Source: The Pharmacia & Upjohn Company, Pre-Clinical Division Title: Understanding the Neurochemistry of the D4 Receptor: Relationship to Schizophrenia and Parkinson's Disease. PI: Patricia A. Broderick, Ph.D. Dates: 9/1/93 - 8/31/95 Award: $35,200. 00 Source: The Pharmacia & Upjohn Company, Clinical Division Title: Neurochemical Mechanisms for Alprazolam, Diazepam and Desipramine. PI: Patricia A. Broderick, Ph.D. Dates: 2/4/92 - 2/4/95 Award: $19,800. 00 Source: The Pharmacia & Upjohn Company, Clinical Division: Educational Award Title: Presentations on Affective Disorders PI: Patricia A. Broderick, Ph.D. Dates: 11/1/92 - 12/31/96 Award: $6,000.00 Source: PSC/CUNY (Professional Staff Congress/The City University of New York) Title: Study of Atypical Neuroleptic Clozapine on Cocaine-Induced Dysfunctional Neurotransmitter Release and Behavior. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/1997 - 12/31/1999 Award: $9,280.00 Source: PSC/CUNY (Professional Staff Congress/The City University of New York) Title: Real Time Dopamine and Serotonin Release in Nucleus Accumbens During Cocaine Withdrawal. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/95 - 12/31/97 Award: $8,500. 00 Source: PSC/CUNY (Professional Staff Congress/The City University of New York) Title: The Effects of Ibogaine and Alpha-cis-Flupenthixol on Cocaine-Induced Biogenic Amine Dysfunction: Preclinical Treatment Strategies. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/92 - 12/31/94 Award: $6,300. 00 Source: NIH, National Institutes of Health, National Institute on Drug Abuse (NIDA) Title: Electrochemical Study of CNS Reward Circuits for Cocaine. PI: Patricia A. Broderick, Ph.D. Dates: 8/1/89 - 7/31/92 Award: $151,554. 00 Source: The Pharmacia & Upjohn Company, Preclinical Division Title: Neurochemical Profiles of Antipsychotic and Anxiolytic Drugs for Clinical Evaluation. PI: Patricia A. Broderick, Ph.D. Dates: 12/15/90 - 12/31/92 Award: $25,000.00 Source: Biomedical Research Support (NIH Supplement) Title: Electrochemical Study of CNS Reward Circuits for Cocaine. PI: Patricia A. Broderick, Ph.D. Dates: 4/1/91 - 3/31/92 Award: $4,000.00 Source: PSC/CUNY (Professional Staff Congress/The City University of New York) Title: An In Vivo Electrochemical Study of Brain Reward Circuits for Cocaine in the Freely Moving Rat. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/89 - 12/31/91 Award: $18,904.00 Source: The Pharmacia & Upjohn Company, Preclinical Division Title: Effects of 5-HT1A Agonists on Serotonin and Norepinephrine Release Measured In Vivo. PI: Patricia A. Broderick, Ph.D. Dates: 1/1/89 - 1/1/91 Award: $22,000.00 Source: The Pharmacia & Upjohn Company, Clinical Division Title: Dopaminergic Activity of Adinazolam. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/89 - 6/30/90 Award: $3,000.00 Source: Biomedical Research Support (NIH Supplement) Title: Electrochemical Study of the CNS Reward Circuits for Cocaine. PI: Patricia A. Broderick, Ph.D. Dates: 4/1/89 - 3/31/90 Award: $2,000.00 Source: Biomedical Research Support (NIH Supplement) Title: In Vivo Electrochemical Study of Dopamine in CNS Neuroanat. Sites Associated with Brain Reward. PI: Patricia A. Broderick. Ph.D Dates: 4/1/87 - 3/31/89 Award: $6,000.00 Source: PSC/CUNY (Professional Staff Congress/The City University of New York). Title: An In Vivo Electrochemical Study of the Reward Circuits for Cocaine in Brain. PI Patricia A. Broderick, Ph.D. Dates: 7/1/87 - 12/31/88 Award: $4,200.00 Source: The Pharmacia & Upjohn Company, Preclinical Division Title: In Vivo Electrochemistry: Novel Dopaminergic Autoreceptor Agonists. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/84 - 6/30/87 Award: $30,000.00 P.A. Broderick , Co-Principal Investigator* and Co-Investigator **: Source: NIH, National Institute on Health * Title: Feasibility Study: Diabetes Research and Training Center Subtitle: Diabetes and Brain Monoamine Metabolism. (P.I's: Drs. Fleisher and Jacoby) Dates: 12/1/83 -11/30/85 Award: $30,000.00 Source: NIDA, National Institute on Drug Abuse** Title: Marijuana & Dopamine/Enkephalin Brain Reward Systems. (P.I.: Dr. Gardner) Dates: 7/1/84 - 6/30/85 Award: $74,859.00 STUDY GRANTS: 1974 New York State Study Grant (Chemistry of Alcohol Abuse), New York University. 1972 National Science Foundation Study Grant (Introductory Microbiology), Indiana U. 1972 National Science Foundation Study Grant (Marine Biology), University of Maine 1972 National Science Foundation Study Grant (Psychopharmacology of Drug Use and Abuse), Vanderbilt U., TN. 1971 National Science Foundation Study Grant (Ecology), Radford College, Virginia 1967 National Science Foundation Study Grant (Chemistry), Pace University, NY.- Email:[email protected]
Nana Yaw Adu-Sarkodie ’99
Education
Ph.D., 1979, St. John's University
M.S., 1970, Fordham University
B.S., 1963, St. Thomas Aquinas College
Postdoctoral Positions:
Dept. of Psychiatry & Neuroscience, Albert Einstein College of Medicine, NY Dept. of Neurology, Cornell University School of Medicine, NY
Research Interests
Development of miniature biosensors for the detection of neurotransmitters and other biologically active compounds such as ascorbic acid, peptides, precursors and metabolites. These BRODERICK PROBE® biosensors allow the study of dynamic changes in neurotransmitters in vivo and in real time, on line with behavioral models as well as on line Neuromolecular Imaging (NMI) with biosensors with cerebral blood flow studies of stroke in animal models.
Studies of cocaine, caffeine, hypoxia, calcium channel blockers, hypotension and nitroglycerin are underway. Ongoing significant advances have been made with these biosensors in human studies in epilepsy patients beginning in 2008 during intraoperative diagnosis of temporal lobe epilepsy with Internal Review Board Approval, NYU, Tisch Hospital , NY.
Pharmacotherapeutic approaches to the treatment of cocaine abuse, caffeine mechanisms, pain, affective disorders, epilepsy, tumors, schizophrenia, Parkinson's disease, post-operative cognitive diseases, drug addiction, oxidative stress, inflammation, cytokines, hypertension, hypoxia, calcium channel blockers, nitroglycerin, ascorbic acid, peptides, stress, enkephalins, dynorphin, morphine, diabetes, Fawn-Hooded animal models, Chediak-Higashi Syndrome.
Publications
Peer-Reviewed Articles
Broderick, P.A., Doyle, W.K., Pacia, S.V., Kuzniecky, R.I., Devinsky, O, and Kolodny, E.H., A clinical trial of an advanced diagnostic biomedical device for epilepsy patients. Journal of Long-Term Effects of Medical Implants, In Press, (2009).
Broderick, P.A., Ho, H., Wat, K. and Murthy, V., Laurate biosensors image brain neurotransmitters in vivo: Can an antihypertensive medication alter psychostimulant behavior? Sensors 8: 4033-4061 (2008).
Broderick, P.A., Studies of oxidative stress mechanisms using a morphine/ascorbate animal model and novel N-stearoyl cerebroside and laurate sensors. J. Neural Transm. 115: 7-17 (2008).
Nunes, J.V. and Broderick, P.A., Novel research translates to clinical cases of schizophrenic and cocaine psychosis. Neuropsychiatric Disease and Treatment 3(4): 475-485 (2007).
Broderick, P.A.; Pacia, S.V. Identification, diagnosis, and treatment of neuropathologies, neurotoxicities, tumors and brain and spinal cord injuries using microelectrodes with microvoltammetry. 2006, U.S. Patent # 7,112,319. Issued, Sept. 26th (2006).
Broderick, P.A. and Hope, O., Monoamines and motor responses are co-deficient in the Fawn-Hooded depressed animal model. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 30: 887-898 (2006).
Simmons, D.A. and Broderick, P.A.. Cytokines, stressors and clinical depression: augmented adaptation responses underlie depression pathogenesis. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 29: 793-807 (2005).
Broderick, P.A., Olabisi, O.A., Rahni, D.N. and Zhou, Y., Cocaine acts on accumbens monoamines and locomotor behavior via a 5-HT2A/2C receptor mechanism as shown by ketanserin: 24 hr follow-up studies. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 28: 547-557 (2004).
Broderick, P.A., Hope, O., Okonji, C., Rahni, D.N. and Zhou, Y., Clozapine and cocaine effects on dopamine and serotonin release in nucleus accumbens during psychostimulant behavior and withdrawal. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 28: 157-171 (2004).
Broderick, P.A., Rahni, D.N. and Zhou, Y., Acute and subacute effects of risperidone and cocaine on accumbens dopamine and serotonin release using in vivo microvoltammetry on line with open-field behavior. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 27: 1037-1054 (2003).
Broderick, P. A. Interieukin 1a alters hippocampal serotonin (5-HT) and norepinephrine (NE) release during open-field behavior in Sprague Dawley animals: Differences from the Fawn-Hooded animal model of depression. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 26: 1355-1372 (2002).
Pacia, S. V., Doyle, W. K. and Broderick, P. A., Biogenic amines in resected human neocortex in patients with neocortical and mesial temporal lobe epilepsy; Identification with in situ microvoltammetry. Brain Research 899:106-111 (2001)
Broderick, P. A., Pacia, S. V., Doyle, W. K. and Devinsky, O., Monoamine neurotransmitters in resected hippocampal subparcellations from neocortical and mesial temporal lobe epilepsy patients: In situ microvoltammetric studies. Brain Research 878:48-63 (2000)
Broderick,P.A., Microelectrodes and their use in a cathodic electrochemical current arrangement with telemetric application. Canadian Patent and PCT # 2,063,607. Issued Nov. 24th(2000).
Broderick, P.A., Microelectrodes and their use in a cathodic electrochemical current arrangement with telemetric application. U.S. Patent # 5,938,903. Issued, Aug. 17th (1999). Broderick, P.A., Microelectrodes and their use in a cathodic electrochemical current arrangement with telemetric application. Hong Kong, The People's Republic of China, Patent # HK 1007350. Issued, Aug. 9th (1999).
Broderick, P. A. and Piercey, M. F., Neurochemical and behavioral evidence supporting (+)-AJ 76 as a potential pharmacotherapy for cocaine abuse. J. Neural Transm. 105: 1307-1324 (1998).
Broderick, P. A. and Piercey, M. F., Clozapine, haloperidol and the D4 antagonist PNU-101387G: In vivo effects on mesocortical, mesolimbic and nigrostriatal dopamine and serotonin release. J. Neural Transm. 105:749-767 (1998).
Broderick, P. A., Hope, O. and Jeannot, P. Mechanism of triazolo-benzodiazepine and benzodiazepine action in anxiety and depression: behavioral studies with concomitant in viro CA1 hippocampal norepinephrine and serotonin release detection in the behaving animal. Prog. Neuro-Psychopharmacol. & Biol. Psychiat. 22:353-386 (1998).
Book Chapters
Simmons, D.A. and Broderick, P.A.. Cytokines, stressors and clinical depression: augmented adaptation responses underlie depression pathogenesis. In: Selective Affective Disorders and Schizophrenia.Prog. Neuro-Psychopharmacol. & Biol. Psychiat.(Eds. Broderick, P.A. and Glazer, W.M.) 29: 793-807 (2005).
Pacia, S.V. and Broderick, P.A., Bioimaging L-Tryptophan in human hippocampus and neocortex subtyping temporal lobe epilepsy with microvoltammetry.In: Bioimaging in Neurodegeneration(Eds. Broderick, P.A., Rahni, D.N. and Kolodny, E.H.) Humana Press Inc., Totowa, NJ, pp. 141-147 (2005).
Broderick, P.A., Rahni, D.N. and Pacia, S.V., Nano-and microimaging surgical anesthesia in epilepsy patients. In: Bioimaging in Neurodegeneration (Eds. Broderick, P.A., Rahni, D.N. and Kolodny, E.H.) Humana Press Inc.., pp. xiii-Totowa, NJ, pp. xiii-xvi (2005).
Broderick, P.A. and Pacia, S. V., Imaging white matter signals in epilepsy patients: A unique sensor technology. In: Bioimaging in Neurodegeneration (Eds. Broderick, P.A., Rahni, D.N. and Kolodny, E.H.) Humana Press Inc., Totowa, NJ, pp.199-206 (2005).
Broderick, P.A., Microsensors detect cocaine neuroadaptation: Serotonin release within basal ganglia is not rhythmic with movement. In: Handbook of Neurotoxicology (Eds. Massaro, E.J., Schardein, J.L., Broderick, P.A., Schlaepfer, T.E. and Mattsson, J.L.) Humana Press Inc., Totowa, NJ, 2: pp.323-367 (2002).
Grants/Contracts
Broderick, P.A. Research Grant, Center for Advanced Technology, CCNY, CUNY, NY State Project, ($7500) (2013).
Broderick, P.A. Travel Award, HEKA Electronics Inc., Nova Scotia, Canada, ($3000) (2012)
Broderick, P.A. Research Grants and Licensing Fee, HEKA Electronics, Inc., NY, Germany, Canada, ($117,000) (2013).
Broderick, P.A. Grants from the Anesthesiology Dept., NYU Langone to support part-time technician and support collaboration on Neuromolecular Imaging, hypoxic hypoxia and cognitive decline post-operatively about $100,000-in personnel and supplies (2007-2010).
Broderick, P.A., NYU Langone: Translational work in vivo during epilepsy surgery. IRB (2008) obtained by Dr. Ruben Kuzniecky, Epileptologist, Director of Research, Comprehensive Epilepsy Center, NYU Langone, Dept. of Neurology. This approved project allows use of BRODERICK PROBE® biosensors (manufactured on site, CCNY, NY and Autolab Potentiostat (Metrohm, aka Brinkmann, LI, NY). Amount, immeasurable (2008-present)
Broderick, P.A. NYU, FACES, Foundation for Children with Epileptic Seizures. Neuromolecular imaging in epilepsy and tumor patients intraoperatively using The BRODERICK PROBE® biosensors. ($35, 000).
Broderick, P. A. FM Kirby Foundation: Anti-Platelet Therapy in Ischemic Stroke: Imaging Real Time Neurochemical Changes in Brain. ($125,000.00, 2008-2011).
Kolodny, E.H., Broderick, P.A. Leon Lowenstein Foundation: Gene Therapy in Parkinson's Disease. ($57,255), Sept. 2007 – Dec., 2009).
Previous Additional Sources of Support (2003-2004):
Broderick, P.A., P.I., Student Scholarship Fund: H.S. Student Training: CNS studies.
Broderick, P.A., P.I., Stevens, Davis, Miller and Mosher, LLC: Patent Consult: CNS studies.
Broderick, P.A., P.I., Pharmacia Upjohn Award: CNS research; psychosis, depression, drug abuse.
Broderick, P.A., P.I., Grant and Consultation Support (2002-2004):Codman & Shurtleff, J&J, Broderick Biotechnology.
Broderick, P.A., P.I., Professional Staff Congress, CUNY (2002-2003): Nitrous and Nitric Oxide studies.
National Institute of Health, Foundation and Industrial Support:
Source: National Institutes of Health, NIGMS: SCORE AWARD.
Title: Normal vs. Psychotic Behavior: Neural Basis for Clozapine.
PI: Patricia A. Broderick, Ph.D.
Dates 02/01/00 - 01/31/03
Award: $475,000.00
Source: Parents against Childhood Epilepsy: P.A.C.E. AWARD.
Title: In Vivo Voltammetry with Microelectrodes for the Detection and Quantification of Neurotransmitters in Epileptogenic Cortex during Epilepsy Surgery.
Co-PI: Patricia A. Broderick, Ph.D.
Co-PI: Steven V. Pacia, M.D.
Dates: 12/15/99 - 8/30/01
Award: $52,568. 00
Source: The Pharmacia and Upjohn Company, (Clinical Division: Educational Award).
Title: Brain Neurotransmitter Signals for Diagnosis and Treatment of Central Nervous System Disorders: Psychotic, Affective, Cognitive and Epileptogenic.
PI: Patricia A. Broderick, Ph.D.
Dates: 9/1/1997-unrestricted time period.
Award: $10,000. 00
Grants: Research Support (1985-1999) (Award amounts are written in direct costs; indirect costs are not shown):
Source: The Aaron Diamond Foundation
Title: The Study of a Neuroimmune Link Between AIDS-Related, Interleukin-1 (IL-1) and the Excitotoxin, Quinolinic Acid: Signal Intercommunication in the Hippocampal Serotonergic Neurotransmitter Circuitry.
PI: Patricia A. Broderick, Ph.D. Co-Inv.: Richard Coico, Ph.D. Dates: 10/15/92 - 1/7/95 Award: $143,500. 00 Source: Foundation for Children with Epileptic Seizures: FACES AWARD. Title: Neurotransmitter Release at the Human Epileptogenic Focus: In Situ Studies. PI: Patricia A. Broderick, Ph.D. Dates: 11/15/96 - 6/30/99 Award: $50,000. 00 Source: The Pharmacia & Upjohn Company, Pre-Clinical Division Title: Understanding the Neurochemistry of the D4 Receptor: Relationship to Schizophrenia and Parkinson's Disease. PI: Patricia A. Broderick, Ph.D. Dates: 9/1/93 - 8/31/95 Award: $35,200. 00 Source: The Pharmacia & Upjohn Company, Clinical Division Title: Neurochemical Mechanisms for Alprazolam, Diazepam and Desipramine. PI: Patricia A. Broderick, Ph.D. Dates: 2/4/92 - 2/4/95 Award: $19,800. 00 Source: The Pharmacia & Upjohn Company, Clinical Division: Educational Award Title: Presentations on Affective Disorders PI: Patricia A. Broderick, Ph.D. Dates: 11/1/92 - 12/31/96 Award: $6,000.00 Source: PSC/CUNY (Professional Staff Congress/The City University of New York) Title: Study of Atypical Neuroleptic Clozapine on Cocaine-Induced Dysfunctional Neurotransmitter Release and Behavior. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/1997 - 12/31/1999 Award: $9,280.00 Source: PSC/CUNY (Professional Staff Congress/The City University of New York) Title: Real Time Dopamine and Serotonin Release in Nucleus Accumbens During Cocaine Withdrawal. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/95 - 12/31/97 Award: $8,500. 00 Source: PSC/CUNY (Professional Staff Congress/The City University of New York) Title: The Effects of Ibogaine and Alpha-cis-Flupenthixol on Cocaine-Induced Biogenic Amine Dysfunction: Preclinical Treatment Strategies. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/92 - 12/31/94 Award: $6,300. 00 Source: NIH, National Institutes of Health, National Institute on Drug Abuse (NIDA) Title: Electrochemical Study of CNS Reward Circuits for Cocaine. PI: Patricia A. Broderick, Ph.D. Dates: 8/1/89 - 7/31/92 Award: $151,554. 00 Source: The Pharmacia & Upjohn Company, Preclinical Division Title: Neurochemical Profiles of Antipsychotic and Anxiolytic Drugs for Clinical Evaluation. PI: Patricia A. Broderick, Ph.D. Dates: 12/15/90 - 12/31/92 Award: $25,000.00 Source: Biomedical Research Support (NIH Supplement) Title: Electrochemical Study of CNS Reward Circuits for Cocaine. PI: Patricia A. Broderick, Ph.D. Dates: 4/1/91 - 3/31/92 Award: $4,000.00 Source: PSC/CUNY (Professional Staff Congress/The City University of New York) Title: An In Vivo Electrochemical Study of Brain Reward Circuits for Cocaine in the Freely Moving Rat. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/89 - 12/31/91 Award: $18,904.00 Source: The Pharmacia & Upjohn Company, Preclinical Division Title: Effects of 5-HT1A Agonists on Serotonin and Norepinephrine Release Measured In Vivo. PI: Patricia A. Broderick, Ph.D. Dates: 1/1/89 - 1/1/91 Award: $22,000.00 Source: The Pharmacia & Upjohn Company, Clinical Division Title: Dopaminergic Activity of Adinazolam. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/89 - 6/30/90 Award: $3,000.00 Source: Biomedical Research Support (NIH Supplement) Title: Electrochemical Study of the CNS Reward Circuits for Cocaine. PI: Patricia A. Broderick, Ph.D. Dates: 4/1/89 - 3/31/90 Award: $2,000.00 Source: Biomedical Research Support (NIH Supplement) Title: In Vivo Electrochemical Study of Dopamine in CNS Neuroanat. Sites Associated with Brain Reward. PI: Patricia A. Broderick. Ph.D Dates: 4/1/87 - 3/31/89 Award: $6,000.00 Source: PSC/CUNY (Professional Staff Congress/The City University of New York). Title: An In Vivo Electrochemical Study of the Reward Circuits for Cocaine in Brain. PI Patricia A. Broderick, Ph.D. Dates: 7/1/87 - 12/31/88 Award: $4,200.00 Source: The Pharmacia & Upjohn Company, Preclinical Division Title: In Vivo Electrochemistry: Novel Dopaminergic Autoreceptor Agonists. PI: Patricia A. Broderick, Ph.D. Dates: 7/1/84 - 6/30/87 Award: $30,000.00 P.A. Broderick , Co-Principal Investigator* and Co-Investigator **: Source: NIH, National Institute on Health * Title: Feasibility Study: Diabetes Research and Training Center Subtitle: Diabetes and Brain Monoamine Metabolism. (P.I's: Drs. Fleisher and Jacoby) Dates: 12/1/83 -11/30/85 Award: $30,000.00 Source: NIDA, National Institute on Drug Abuse** Title: Marijuana & Dopamine/Enkephalin Brain Reward Systems. (P.I.: Dr. Gardner) Dates: 7/1/84 - 6/30/85 Award: $74,859.00 STUDY GRANTS: 1974 New York State Study Grant (Chemistry of Alcohol Abuse), New York University. 1972 National Science Foundation Study Grant (Introductory Microbiology), Indiana U. 1972 National Science Foundation Study Grant (Marine Biology), University of Maine 1972 National Science Foundation Study Grant (Psychopharmacology of Drug Use and Abuse), Vanderbilt U., TN. 1971 National Science Foundation Study Grant (Ecology), Radford College, Virginia 1967 National Science Foundation Study Grant (Chemistry), Pace University, NY.- Email:[email protected]
Rajeev Babbar '89
Bio:
Dr. Abreu began a life-long love of helping others with their health as an Emergency Medical Technician. Soon thereafter she manifested her desire to teach others as an EMT lab instructor. Having a passion for holistic wellness and healthcare, she became a Doctor of Chiropractic with a focus on helping patients restore and maintain good health. Dr. Abreu has further specialized in nutritional assessment and counseling, and is a Certified Health Coach by the National Society of Health Coaches. After 14 years of private practice, she once again embraced her love of teaching here at the CUNY School of Medicine.
Education:
Doctor of Chiropractic, 1999, Life University, Georgia
Certified Health Coach, 2015, National Society of Health Coaches
- Phone:212-650-6579
- Email:[email protected]
Joanne Fernández-Booker ’12
Bio:
Samantha Barrick is a Lecturer and Director of Humanities in Medicine at the Sophie Davis School of Biomedical Education. She is the Course Director for the Narrative Medicine FIQWS Course and Health, Medicine, and Society 1 (HMS 1). Professor Barrick coordinates and facilitates narrative medicine sessions with faculty, students and staff at Sophie Davis, and trains student mentors to do the same. She is helping to develop a humanities thread throughout the curriculum. She also teaches in the Program of Narrative Medicine at Columbia University and is a poet & writer.
Education:
M.S., 2010, Columbia University, New York
B.A., 1999, New School for Social Research, New York
Courses Taught:
Narrative Medicine FIQWS Course
Health, Medicine and Society 1
Training for Wellness and Reflective Practice
Socio-Medical Science
Research Interests:
Research on validated instruments to capture empathy, professionalism and burnout.
Publications
- "Infinity and the Construction of Safe Space." In Queering Sexual Violence: Radical Voices from Within the Anti-Sexual Violence Movement, ed. Jennifer Patterson: Magnus Books, New York, NY. Forthcoming 2014
- "Bats" and "20 pinks of the body." Poems. The Ledge Magazine, Belmont, NY. Spring, 2011
- "On the Road." Cover article and five poems, Philadelphia City Paper, Philadelphia, PA. 2006
- Jelly. Chapbook of poems with accompanying artwork of Theodore Harris and Beandrea Davis. TigerMonkey Alliance, Inc., Philadelphia, PA. 2005
- Phone:212-650-6629
- Email:[email protected]
Rick Gustave ’06 MD, MPH
Education:
Ph.D. 1991 UMDNJ-Robert Wood Johnson Medical School
B.S. 1984 Universidad Austral de Chile
Research Interests
Dr. Cortes's laboratory studies the mechanisms of V(D)J recombination and non-homologous end joining (NHEJ) and investigates the etiology of human diseases related to these processes. As Dr. Cortes develops these studies, she mentors new generations of students, postdocs and research assistants, giving them solid foundations to become outstanding contributors in their individual careers.
V(D)J recombination and NHEJ are essential for the generation of antibodies, T cell receptors and to maintain genomic stability. Early studies done by her group demonstrated that RAG2, one of the specific components of V(D)J recombination, bridges the RAG recombinase with chromatin through histone interaction; showing that mutations in the PHD domain of RAG2-identified in patients with SCID and Omenn Syndrome-affected RAG2 stability, cellular localization, and histone interaction. This work defined novel mechanisms of RAG2 mediated immunodeficiency. More recently, her team has identified novel roles of Artemis and Ligase IV, two DNA repair proteins, on V(D)J recombination and DNA repair by showing that Artemis facilitates efficient V(D)J recombination and DNA repair through its interaction with DNA Ligase IV and DNA-PKcs. The specificity, structural, and biophysical properties of the indicated interaction were defined at a molecular level using state of the art technology.
The current focus of the laboratory is on elucidating the molecular mechanisms that control DNA Ligase IV function and on exploring the potential applications of these findings in the modulation of DNA repair. In addition, her laboratory continues to develop national and international collaborations to investigate yet uncharacterized molecular mechanisms of immunodeficiency.
Courses Taught
MED204/MED305 Molecules to Cells – Course co-Director and lecturer
Organ Systems: PBL facilitator
Publications
- Maffucci, P., Chavez, J., Jurkiw, T.J., O’Brien, P.J., Abbott, J.K., Reynolds, P.R., Worth, A., Notarangelo, L.D., Felgentreff, K., Cortes, P., Boisson, B., Radigan, L., Cobat, A., Dinakar, C., Ehlayel, M., Ben-Omran, T., Gelfand, E.W., Casanova, J-L., Cunningham-Rundles, C. (2018). DNA LIG1 Mutations lead to a Spectrum of Immune Deficiencies. J Clin. Invest. In press.
- Charlier, C., Bouvignies, G., Pelupessy, P., Walrant, A., Marquant, R., Kozlov, M., De Ioannes, P., Bolik-Coulon, N., Sagan, S., Cortes, P., Aggarwal, A., Carlier, L., Ferrage, F. (2017). Structure and dynamics of an intrinsically disordered protein region that partially folds upon binding by chemical-exchange NMR. J. Am. Chem. Soc. 139 (35): 12219-12227.
- Francis, D. B., Kozlov, M., Chavez, J., Chu, J., Malu, S., Hanna, M., and Cortes, P. (2014). DNA Ligase IV regulates XRCC4 nuclear localization. DNA Repair 21, 36-42.
- Van Til NP, Sarwari, R., Visser, T.P., Hauer, J., Lagresle-Peyrou, C., van der Velden, G., Malshetty, V., Cortes, P., Jollet, A., Danos, O., Cassani, B., Zhang, F., Thrasher, A.J., Fontana, E., Poliani, P.L., Cavazzana, M., Verstegen, M.M., Villa, A., and Wagemaker, G. J. (2014). Recombination-activating gene 1 (Rag1)-deficient mice with severe combined immunodeficiency treated with lentiviral gene therapy demonstrate autoimmune Omenn-like syndrome. Allergy Clin Immunol 133, 1116-1123.
- De Ioannes, P., Malu, S., Cortes, P.*, and Aggarwal, AK.* (2012). Structural Basis of DNA Ligase IV-Artemis Interaction in Nonhomologous End-Joining. Cell Reports 2, 1505-15012. *corresponding authors.
- Mayer, L.*, Lira, S., Ting, A., and Cortes, P. (2012). Introduction to the special issue on Immunology at Mount Sinai. *corresponding author. Immunol Res. 54, 1-3.
- Malu, S., Malshetty, V., Francis, D., and Cortes, P. (2012). Role of non-homologous end joining in V(D)J recombination. Immunol Res. 54, 233-246.
- Malu, S., De Ioannes, P., Kozlov, M., Green, M., Francis, D., Hanna, M., Pena, J., Escalante, C.R., Kurosawa, A., Erdjument-Bromage, H., Tempst, P., Adachi, N., Vezzoni, P., Villa, A., Aggarwal, A., and Cortes, P. (2012). Artemis C-terminal region facilitates V(D)J recombination through its interactions with DNA Ligase IV and DNA-PKcs. J. Exp. Med. 209 (5), 955-963.
- Couedel, C., Roman, C., Jones, A., Vezzoni, P., Villa, A., and Cortes, P. (2010). Mutations isolated from patients with SCID and Omenn Syndrome reveal the central role of RAG2 PHD domain in regulating V(D)J recombination. J Clin. Invest. 120 (4), 1337-1344.
- Matangkasombut, P., Pichavant, M., Saez, D.E., Giliani, S., Mazzolari, E., Finocchi, A., Villa, A., Cortes, P., Umetsu, D.T., and Notarangelo, L. (2008). Lack of iNKT cells in patients with combined immune deficiency due to hypomorphic RAG mutations. Blood 111, 271-274.
- Phone:212-650-7485
- Email:[email protected]
Marilyn Huamantla ‘17
Bio:
A native New Yorker and Family Physician with 30 years' experience working with underserved communities in the Bronx and Philadelphia. After graduating from the Albert Einstein College of Medicine, Dr Deen completed an internship and residency in Family Medicine at Montefiore Medical Center’s Residency Program in Social Medicine. Deciding as an undergraduate student that he wished to teach nutrition to physician. He obtained graduate training at Columbia University College of Physicians and Surgeons Institute of Human Nutrition before attending medical school. He began teaching nutrition while still a medical student and has been involved in teaching students, residents, and faculty on local, regional and national levels. Recognizing the central role of doctor-patient communication in helping patients adopt healthier diets, he has studied and taught models of behavior change counseling and helped to develop and teach patient engagement and activation. His career has been devoted to training primary care clinicians for urban practice.
Prior to joining the Sophie Davis community he was the Director of Medical Student Education for the Department of Family and Social Medicine at the Albert Einstein College of Medicine. Dr Deen has post-graduate training in Mind-Body Medicine, Meditation, Lifestyle Medicine, Acupuncture, Health Coaching, and Functional Medicine. He is board certified in both Family Medicine and Integrative and Holistic Medicine. Here at the CUNY School of Medicine he teaches lifestyle medicine, nutrition, health coaching, and medical interviewing. He has authored numerous scientific publications, edited the Complete Guide to Nutrition in Primary Care, and written nutrition books for lay audiences with my nutritionist partner Dr. Lisa Hark. In addition to medical education, his interests include health disparities, social justice, integrative pain management, improving physician-patient communication, stress management for patients and professionals, medical student resiliency, and self-reflection as a learning technique.
Courses Taught
Patient-Doctor
Nutrition
Practice of Medicine 1 and 2
Research Interests
Nutrition
Doctor-Patient Communication
Publications
Kulick D, Deen D. Specialized Nutrition Support Amer Fam Phys 2011;82(2):173-183.
Lu, WH, Deen D, Gold MR. Activating Community Health Center Patients in Developing Question-Formulation Skills: A Qualitative Study. Health Educ Behav accepted 2010.
Deen D, Lu WH, Rothstein D, Santana L, Gold MR. Asking Questions: The effect of a brief intervention in community health centers on patient activation. Patient Educ Couns 2010 e-pub ahead of print
McKee D, Deen D, Blank A, Maher S, Fornari A. Lessons Learned from Implementation of a Family-Focused Lifestyle Change Intervention in Urban Primary Care. Patient Education & Counseling. 2010;79(3):299-305.
Kulick D, Hark L, Deen D. Follow-up after Bariatric Surgery: The Role of the Dietitian. J Am Diet Assn 2010;110(4):593-599.
McKee D, Deen D, Blank A, Maher S, Fornari A. Lifestyle Change Counseling to Prevent Obesity Among Preschool Children. Ann Fam Med. 2010;8:249-255.
Laur C, Ball L, Ray S, et al. Proceedings of the inaugural International Summit for Medical Nutrition Education and Research. Public Health 2016
Deen D, Chang A, Miranda M. Assessment of attitudes regarding access to healthy diet and physical activity resources in an urban community health center population. Annals of Community Medicine and Practice 2015;1(2):1006 (June)
Hark L, Deen D, Morrison G. Learner-Directed Nutrition Content for Medical Schools to Meet LCME Standards, J Biomed Educ http://www.hindawi.com/journals/jbe/aa/469351/
Lenders CM, Deen D, Bistrian B, Edwards MS, Seidner DL, McMahon MM, Kohleimer M, Krebs N. Residency and Specialties Training in Nutrition: A Call for Action. American Journal of Clinical Nutrition May 2014 ePub ahead of print 073528
Maranda M, Deen D, Elshafey S, Gold MR. Response to a Patient Activation Intervention among Spanish-speaking Patients at a Community Health Center in New York City. Journal of Health Care for the Poor and Underserved 2014;25(2):591-604.
Deen D, Lu WH, Weintraub MR, Maranda, MJ, Elshafey S, Gold, MR. The Impact Of Different Modalities For Activating Patients In A Community Health Center Setting. Patient Education and Counseling 2012. http://dx.doi.org/10.1016/j.pec.2012.04.012
Indyk D, Deen D, Fornari A, Santos MT, Lu WH, Rucker L. The influence of longitudinal mentoring on medical student selection of primary care residencies BMC Medical Education 2011;11:27. doi:10.1186/1472-6920-11-27
Lu, WH, Deen D, Gold MR. Activating Community Health Center Patients in Developing Question-Formulation Skills: A Qualitative Study. Health Education and Behavior 2011;38(6):637-45.
- Phone:212-650-7784
- Email:[email protected]
David Kaufman ’80
Education
Ph.D 1997 New York Medical College
B.A.,1966, Brooklyn College
Research Interests
Transmembrane signaling via G protein-coupled receptors and plasticity of these receptors in health and disease.
Role of MAP kinases in GPCR signaling.
Role of altered cellular signal transduction in the etiology of bipolar illness and in the mechanism of action of mood stabilizers.
Characterization of a novel brain dopamine receptor that couples to phospholipase C.
Molecular mechanisms involved in mediating the morphological and behavioral effects of in utero exposure to cocaine.
Publications
Guo L, Chen Y, Zhao R, Wang G, Friedman E, Zhang A, and Zhen X. Allosteric modulation of sigman-1 receptors elicits anti-seizure activities. Br J pharmacol. 2015 Aug;l 72(16):4052-65
Fontanesi C, Kvint S, Frazzitta G, Bera R, Ferrazzoli D, Di Rocco A, Rebholz H, Friedman E, Pezzoli G, Quartarone A, Wang HY, and Ghilardi MF. Intensive rehabilitation enhances lymphocyte BDNF-TrkB signaling in patients with parkinson's disease. Neurorehabil Neural repair. 2015 Aug 7
Carmona, N.M, Frankfurt, M, and Friedman, E. Effects of Cocaine and Estrogen on BDNF-Trk B Signaling in hippocampi of ovariectomized rats. Applied Science, 2, 2016 Jan
Castello, J., Ragnauth, A., Friedman, E. and Rebholz, H. CK2-An Emerging Target for Neurological and Psychiatric Disorders. Pharmaceuticals 2017
Cortes M., Malave L., Castello J., Flajolet M., Cenci M. A., Friedman E. and Rebholz H. Ck2oppositely modulates L-DOPA induced dyskinesia via striatal projection neurons expressing Dl- or 02-receptors. Journal of Neuroscience 37 (49} 11930-11946, 2017
Castello J.,Le Francois B., Fajolet M., Greengard P., Friedman, E., and Rebholz H. CK2 regulates 5-HT4 receptor signaling and modulates depressive-like behavior. Molecular Psychiatry 10, 1038- 2017
Le Franois, B, Zhang, L, Mahajan, G.J., Stockmeier, C.A., Friedman, E and Albert. P.R. Alternative splicing of the human 5-HT1A mRNA 3'- UTR enhances its stability and is impaired in Major depression (submitted)
Chan, Y.C , , Singh I., Lee E.J., Olufawo M., ,Magnuson H., Zohaib M., Anazco-Ayala A., Pabla A., Friedman E.,. Banerjee S.P. Operational Characteristics of Inhibition of Electricall Evoked Potentials in Rat Medial Prefrontal Cortical Slices by Ro25-6981 and TCN-213 and Their Respective Modulation by Coapplied Taurine (Submitted)
Bakshi K., Parihar R., Goswami SK, Walsh M, Friedman E, Wang Hy. Prenatal cocaine exposure uncouplesmGluR1 from Homer1 and Gq Protenins. pLoS One. 2014
Chan, C.Y., Sun, H.s, Shah, S.M., Agovic, M.S., Friedma, E., Banerjee, S.P. Modes of direct modulation by taurine of the glutamate NMDA receptor in the rat cortex. Eur J Pharmacology. 2014 April 2015; 728:167-175
Mu Y, Ren Z., Jia J, Gao B., x. Inhibition of phosphodiesterase 10A attenuated morphine-induced conitioned place preference: Mol Brain, 2104 Sep 25; 7:70
Chan ,CY, Singh, I, Magnuso H, Zohaib M, Bakshi KP, Le Francios B, Anazco-Ayala A, Lee EJ, Tom A, YeeMon K, Ragnauth A, Friedman E, and Banerjee SP. Taurine targets the GluN2b-Containig NMDA receptor Subtype. Adv. Exp. Med Biol. 2015; 803:531-44
- Phone:212-650-6696
- Email:[email protected]
Ahmed Saleh ’08
Bio:
Dr. Erica Friedman is physician board certified in Internal Medicine and Rheumatology. Since finishing her Rheumatology fellowship, she has always worked at academic medical centers including the NYU School of Medicine, New York Medical College and the Icahn School of Medicine at Mount Sinai. In addition to being a practicing Rheumatologist, she did clinical research focusing on Lyme Disease.
Dr. Friedman has been involved in medical student education for over 25 years. In her present position as Deputy Dean, she has oversight of the curriculum, assessments, offices of academic affairs, registrar, admissions, learning resource center and student affairs. Dr Friedman is Faculty lead for the LCME accreditation process. Dr. Friedman is also the Principal Investigator (PI) on a three year American Medical Association (AMA) funded grant that is part of the AMA Accelerating Change in Medical Education Consortium. She is also co-PI with Dr. Terri Watson on a West Harlem Development Corporation grant to create a health professions pipeline program at the A Phillip Randolph High School that is adjacent to the CCNY campus. She is also a co-investigator on a Memorial-Sloan Kettering NIH/NCI P20 grant to implement curricula to eliminate tobacco disparities. She is an associate editor for MedEdPORTALand a reviewer for Academic Medicine, Annals of Internal Medicine, and Teaching and Learning.
Research Interests
Recognition and Communication of Medical Errors
Assessing Medical Student Communication Skills: Focus on Culture Competence.
Enhancing Education for Chronic Illness Care.
Data Smog and Marketing Fog: A Critical Skills Curriculum to Educate Health Professionals about Rational Prescribing.
Improving Hospitalized Patient Satisfaction and Safety.
Publications
Smith, K.L., Petersen, D.J., Soriano, R., Friedman, E. and Bensinger, L 2007 Training tomorrow's teachers today: A national medical student teaching and leadership retreat. Medical Teacher. 4:328-34.
Cohen, B., Friedman, E., Zier, K 2008 Publications by students doing a year of full-time research: what are realistic expectations? Am J. of Med. 121:545-548.
Anker, A., Feeley, T.H., Friedman, E. and Kruegler, J 2009 Teaching organ and tissue donation in medical and nursing education: a needs assessment. Progress in transplantation.19:343-348.
Griffith, C.H. 3rd, Wilson, J.F., Haist, S.A., Albritton, T.A., Bognar, B.A., Cohen S.J., Hoesley C.J., Fagan M.J., Ferenchick, G.S., Pryor, O.W., Friedman, E., Harrell, H.E., Hemmer, P.A., Houghton, B.L., Kovach, R., Lambert, D.R., Loftus, T.H., Painter, T.D., Udden, M.M., Watkins, R.S., Wong, R.Y 2009 Internal medicine clerkship characteristics associated with enhanced student examination performance. Acad. Med. 84:895-901.
Feeley, T.H., Anker, A.E., Soriano, R.P. and Friedman, E 2010 Using standardized patients to educate medical students about organ donation. Communication Education. 59:249-262.
Friedman E., Muller, D., Rose, S., Sainte, M 2010 Mount Sinai School of Medicine. Acad. Med. 85: S370-S374.
Friedman, E., Sainte, M. and Fallar, R 2010 Taking note of the perceived value and impact on medical student chart documentation on education and patient care. Acad. Med. 85:1440-1444.
McCulloch, C., Marango, S. P., Friedman, E. and Laitman, J. T 2010 Living Anatomy: Teaching and learning musculoskeletal anatomy through yoga and Pilates. Anatomical Sciences Education. 3:279–286.
Triola, M., Friedman, E., Cimino, C., Geyer, E.M., Wiederhorn, J., Mainiero, C 2010 Health Information technology and the medical school curriculum. American Journal of Managed Care. (3 Suppl) 16:sp54-56.
Friedman, E., Karani, R. and Fallar, R. 2011 Regulation of medical student work duty hours: A national survey of deans. Acad. Med. 86:30-33.
Phyllis, S., and Friedman, E. 2011 Clinico-Histologic Conferences: histology and disease. Anatomical Sciences Education. 5:55-61.
Mazurkiewicz, R., Friedman, E., Karani, R., and Lin, J. 2012. Expectations for Medical Student Work Hours in Inpatient Clinical Clerkships. Teaching and Learning in Medicine: 25: 2; 134-140.
Favia, A., Frank, L., Gligorov, N., Birnbaum, S., Cummins, P., Ferguson, K., Mendis, K., Friedman, E., and Rhodes, R. A model for the assessment of medical students' competency in medical ethics. American Journal of Bioethics. Jan 25, 2013. DOI:10.1080/21507716.2013.768308.
Arora, V., Eastment, M., Bethea, E., Farnan, J., and Friedman, E. 2013. Participation and Experience of Third-Year Medical Students in Handoffs: Time to Sign Out? J. Gen. Int. Med. April 18, 2013. DOI: 10.1007/s11606-012-2297-9.
Martos, A.J., Pircha,Y.S., Oladele, M., Erves, J., Dorn, J. and Friedman, E. 2017.An innovative educational pipeline programme for under-represented youth: the Sophie Davis Biomedical Education/CUNY School of Medicine model. Education for Primary Care. Feb 9, 2017. http://dx.doi.org/10.1080/14739879.2017.1289480
Chang, D., Mann, M., Sommer, T., Fallar, R., Weinberg, MS, and Friedman, E. Using Standardized Patients to Assess Hospitalist Communication Skills". J. Hosp. Med. 2017 July;12(7):562-566.
Book Chapters
Friedman Asch E. and. L. Smith. 1999 Osteoporosis. In: Diagnostic Strategies for Common Medical Problem, 2nd Edition. American College of Physicians Press, Philadelphia, PA. pp. 438-449.
Friedman, E. 2006 Osteoporosis. In: Diagnostic Strategies for Common Medical Problems.American College of Physicians. 2nd Edition, revised. Philadelphia, PA. pp. 437-438.
Friedman, E. 2007 Gout. In: First Exposure: Internal Medicine Clerkship Ambulatory Medicine. McGraw-Hill. 1st Edition. New York, NY. pp. 337-341.
Friedman, E. 2007 Infectious Arthritis. In: Internal Medicine Clerkship Inpatient Medicine. McGraw-Hill. New York, NY. pp. 407-412.
Friedman, E. 2007 Chest pain training problems. In: Clerkship Directors in Internal Medicine. Sub-internship. Curriculum training module. Revision. Alliance for Academic Internal Medicine.4:4-36.
Rhodes, R., Friedman, E. 2010 What you need to know about medical errors. In: Surviving Health Care:A manual for patients and their families. Cambridge University Press. New York, NY. pp. 56-68.
Friedman, E., Koestler, J. 2010 Standardized interactive multi-station assessments: A guide to medical education in the teaching hospital. In: Association for Hospital Medical Education, 4th Edition. Cambridge University Press. New York, NY. pp. 337-344.
Friedman, E. 2012 The Competencies. In: Medicine: A Competency Based Companion. Saunders and Elsevier. Philadelphia, PA.
- Phone:212-650-7699
- Email:[email protected]
Roslyn Schneider ’84 MD, MSc
- Email:[email protected]
Tracey Straker ’88 MD, MPH
- Email:[email protected]
Jameela J. Yusuff ’99
Bio:
Dr. Gottlieb's research group is studying and characterizing bacteriophage f12, one of the newly identified members of the family Cystoviridae.These viruses contain a genome consisting of three segments of double-stranded RNA (dsRNA). Their mechanism of RNA packaging, replication and transcription is similar to that of the Reoviridae of which one member, rotavirus, is a major cause of infant gastroenteritis. To date, the cystoviruses are the only segmented dsRNA viruses that can be manipulated by recombinant genetic techniques, making them an excellent model for the study of the molecular biology of viruses of this type.
The laboratory has cloned and sequenced the three genomic segments and identified the viral genes. This analysis has better defined the evolutionary relationships among the members of this virus family. The genes of the virus have been expressed from the cDNA copies of the genome in E. coli and the viral proteins are now being studied, in particular the viral RNA-directed RNA polymerase P2. This study contributes to the understanding of the mechanism of viral RNA packaging and replication.
In a collaborative study with Dr. Spatz, the research group is investigating the role of the Epstein Barr Virus (EBV) in the etiology of Systemic Lupus Erythematosus (SLE). This research project focuses on characterizing the anti-double stranded DNA (dsDNA) response in mice that express the viral Epstein Barr Nuclear Antigen-1 (EBNA-1). The expression of this antigen in animals has been achieved through the use of DNA-based vaccination of recombinant plasmids. The establishment of this in vivo model enabled us to demonstrate that the inoculated mice produced antibodies to autoantigens associated with SLE.
- Phone:212-650-7709
- Email:[email protected]
Bio:
Dr. Sanna M. Goyert is a Medical Professor at the CUNY School of Medicine / Sophie Davis School of Biomedical Education and the former Chair of the Department of Pathobiology (aka Microbiology and Immunology). Previously she was an Associate Professor of Medicine and Pathology at New York University School of Medicine and Director of the Laboratory of Innate Immunity at the Feinstein Institute for Medical Research at North Shore-LIJ Health Systems in Manhasset, New York.
Dr. Goyert is an internationally renowned scientist studying innate immune mechanisms of defense against bacterial pathogens and innate immune receptors in neurodegenerative diseases. Dr. Goyert has published more than 100 research papers and book chapters and is a former recipient of the prestigious Stohlman Scholars award from the Leukemia Society of America. She has been continuously funded by the National Institutes of Health (NIH) for 26 years. Dr. Goyert began her research career by producing monoclonal antibodies that she used to identify and characterize a membrane protein that was at that time a new, second class of HLA antigens that she named HLA-DS for HLA-D-region, Second locus and that was subsequently renamed by WHO as HLA-DQ, currently a very well-known and important family of HLA antigens. These molecules are important not only in transplantation, but also in contributing to the susceptibility to autoimmune diseases. She further used these antibodies to define polymorphisms in HLA-DQ. The identification of HLA-DQ was a breakthrough in this area, particularly since other leaders in this field thought, at the time, that while mice had two Class II antigen families, humans only had 1 family. HLA-DQ is now a major antigen required for matching for transplants; some members of this family also show important correlations in susceptibility to autoimmune diseases.
Dr. Goyert’s second major research accomplishment was the identification of a human gene known as CD14 that plays a prominent role in a disease called septic shock that kills more than 500,000 Americans annually. Dr. Goyert's seminal work showed that mice genetically engineered to lack the CD14 gene are resistant to septic shock caused by E. coli. Dr. Goyert holds two major patents associated with her work on innate immunity that are currently licensed to several companies aiming to further the therapeutic potential of these discoveries.
Dr. Goyert's current work focuses on investigating the role of innate immune receptors in the brain and their functional contribution to neurodegenerative diseases.
Education
Ph.D., 1983, New York University School of Medicine, New York, NY
B.S., 1968, University of Cincinnati, Cincinnati, Ohio
Research Interests
Role of innate immune receptors in neurodegenerative diseases
Identification and functional role of the interaction of innate immune receptors with endogenous ligands.
Continuing studies of innate immune receptors in severe infection.
- Phone:212-650-7773
- Email:[email protected]